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There is plenty of bisexual content there too. Some gams can be downloaded as well. Easy to navigate and tagged with specific choices makes surfing for game content simple and fun. The games are flash based which makes playable anywhere at any time. The bones and the brain are two important tissues in humans where the primary effect of testosterone is by way of aromatization to estradiol.

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In the bones, estradiol accelerates ossification of cartilage into bone, leading to closure of the epiphyses and conclusion of growth. In the central nervous system, testosterone is aromatized to estradiol. Estradiol rather than testosterone serves as the most important feedback signal to the hypothalamus especially gamss LH secretion.

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Like other steroid hormones, testosterone is derived from cholesterol see figure. Testosterone is also synthesized in far requiring total quantities in women by the adrenal glands, thecal cells of the ovariesand, during pregnancyby the placenta.

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Like most hormones, testosterone is supplied to target tissues in the blood where much of it is transported bound to a specific plasma proteinsex hormone-binding globulin SHBG. In males, testosterone is synthesized primarily in Leydig cells. The amount of testosterone synthesized is regulated by the hypothalamic—pituitary—testicular axis see figure to the right.

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These latter two hormones stimulate the testis to synthesize testosterone. The plasma protein binding of testosterone is Testosterone is used as a medication for the treatment of males with too little or no natural testosterone productioncertain forms of breast cancer[10] and gender dysphoria in transgender men.

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This gay sex games not requireing flash or adobe known as hormone replacement therapy HRT or testosterone replacement therapy TRTwhich maintains serum testosterone levels in the normal range. Decline of testosterone production with age has led to interest in androgen replacement therapy. Testosterone is included in the World Health Organization's list of essential medicineswhich are the most important medications needed in a fflash health system.

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Suffering the ridicule of his colleagues, he abandoned his work on the mechanisms and effects of androgens in human beings. Koch, established dice sex games for the access to a large source of bovine testicles — the Chicago stockyards — and recruited students willing to endure the tedious work of extracting their isolates.

Gay sex games not requireing flash or adobe chemical synthesis of testosterone from cholesterol was achieved in August that year by Butenandt and Hanisch. Wettstein, published their synthesis of testosterone. This also made it obvious that additional modifications on the synthesized testosterone could be made, i.

The partial synthesis in the s of abundant, potent testosterone esters permitted the characterization of the hormone's effects, so that Kochakian and Murlin were able to show that testosterone raised nitrogen retention a mechanism central to anabolism in the dog, after which Allan Kenyon's group [] was able to demonstrate both anabolic and androgenic effects of testosterone propionate in eunuchoidal gay sex games not requireing flash or adobe, boys, and women.

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The period of the early s to the s has been called alien planet sex games Golden Age of Steroid Chemistry", [] and work during this period progressed quickly. Research in this golden fkash proved that this newly synthesized compound—testosterone—or rather family of compounds for many derivatives were developed from towas a potent multiplier of gay sex games not requireing flash or adobe, strength, and well-being.

Testosterone is observed in most vertebrates. Testosterone and the classical nuclear androgen receptor first appeared in gnathostomes jawed vertebrates.

From Wikipedia, the free encyclopedia.

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This article is about testosterone as a hormone. For its use as a medication, see Testosterone medication. For other uses, see Testosterone disambiguation. Hormones and sexual arousal. Williams Textbook of Endocrinology. Therapeutics and Clinical Risk Management.

Frontiers of Hormone Research. Biosynthesis, transport, metabolism and non-genomic actions".

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Action, Deficiency, Substitution 4th ed. The Journal of Clinical Endocrinology and Metabolism.

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Heroes, rogues, and lovers: American Society of Health-System Pharmacists. Retrieved 3 September Archives Internationales de Physiologie, de Biochimie et de Biophysique. The European Journal of Neuroscience. Journal of Pediatric Nursing. Ganong's Review of Medical Physiology 24 ed. The Journal of Biological Chemistry. Journal of Personality and Social Psychology. Archived from the original PDF on April 19, The Journal of Sexual Medicine.

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Clinical Interventions in Aging. American Journal of Human Biology.

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The Journal of Endocrinology. Archives of Sexual Behavior. Evolution and Human Behavior.

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Implications for Sexual and Social Behavior". Current Directions in Psychological Science. Archives of General Psychiatry.

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International Journal of Impotence Research. Handbook of crime correlates. Direct analysis of candidate genes in impulsive disorders. Bock G, Goode J, eds. Genetics of Criminal and Antisocial Behaviour.

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